Enhances skin tone, texture, and resiliency. Diminishes appearance of fine lines and coarse wrinkles. Encapsulated with PhytoShield™ Complex, an antioxidant complex, enhancing skin texture and minimizing irritation. Apply In the evening after cleansing and toning and before applying your moisturizer. If a retinol product has never been used before, begin twice a week 2-3 days apart, gradually increasing frequency to every other night, and then advancing to each evening or as tolerated.